Arginine vasopressin (AVP)
精氨酸血管加壓素
Vasopressin, also called antidiuretic hormone (ADH), arginine vasopressin (AVP)
or argipressin,[5] is a hormone synthesized as a peptide prohormone in neurons
in the hypothalamus, and is converted to AVP.
加壓素,也稱為抗利尿激素(ADH),精氨酸加壓素(AVP)或Argipressin,
[5]是一種合成為下丘腦神經元中肽激素的激素,並被轉化為AVP。
Ascorbate-dependent vasopressor synthesis
抗壞血酸(維它命C)依賴的血管加壓合成
Ascorbate is a cofactor for the copper-containing enzyme peptidylglycine
α-amidating monooxygenase (PAM) that is required for the endogenous synthesis
of vasopressin [61].
抗壞血酸是內源性合成加壓素所必需的含銅酶肽基甘氨酸α-酰胺化單加氧酶(PAM)的輔助因子[61]。
The carboxy-terminal glycine residue of the vasopressin precursor subsequently
undergoes post-translational modification by the ascorbate-dependent enzyme PAM
to generate the active carboxy-amidated hormone (Fig. 3).
加壓素前體的羧基末端甘氨酸殘基隨後通過抗壞血酸依賴性酶PAM進行翻譯後修飾,
以生成活性的羧基酰胺化激素(圖3)。
總結以上:
不管是缺少催產素還是加壓素造成沒有忠誠度
缺少的都是維它命C
不過由於都需要靠含銅酶肽基甘氨酸α-酰胺化單加氧酶(PAM)
維它命C可以參考